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Hyponatremia from Oxcarbazepine and Carbamazepine Neurol 65:1976-1978, Dong,X.,et al, 2005 See this aricle in Pubmed Article Abstract The authors examined sodium concentrations from 97 oxcarbazepine-treated (OXC) and 451 carbamazepine-treated (CBZ) patients with epilepsy using cross-section and follow-up studies. The frequency of hyponatremia (Na+ ?134 mEq/L) was 29.9% among OXC-treated patients and 13.5% among CBZ-treated patients (p < 0.0001). Hyponatremia (Na+ ?128 mEq/L) was severe: 12.4% of OXC-treated patients and 2.8% of CBZ-treated patients (p < 0.001). Advanced age was a risk factor for hyponatremia. Hyponatremia, once present, persisted in both groups.

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(click to filter results - removes previous filter) adverse drug reaction anticonvulsants anticonvulsants,untoward effects of carbamazepine carbamazepine,toxicity hyponatremia old age,neurology of oxcarbazepine prognosis risk factors

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